Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Drug interactions may change how your medications work or increase your risk for serious side effects. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. I used to get a different type but my . ByDr. IQVIA [NSP Audit from MAT November 2013 to November 2018]. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Potential injection site discoloration has happened. The following lists contain some of the key side effects that may occur while taking Injectafer. administered at your doctors office or an infusion center. Venofer injection contains iron sucrose, a form of the mineral iron. Some people only need one treatment course of Injectafer. You may report side effects to FDA at 1-800-FDA-1088. So theres no recommended pediatric dosage for Injectafer. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. Injectafer begins working as soon as it enters your body. Do not double the dose to catch up. Otherwise, call a poison control center right away. Injectafer is a brand-name prescription drug. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. Do not start, stop, or change the dose of any drug without checking with your doctor. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. There isnt a known interaction between Injectafer and alcohol. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. 2. With IDA, you have low hemoglobin levels. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. treatment schedule in further detail. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Injectafer should be stored between 68F to 77F (20C to 25C). Dizziness. Venofer pregnancy and breastfeeding warnings. Youll receive doses of either drug by a healthcare professional at a medical facility. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. This test measures the amount of hemoglobin in your blood. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Injectafer contains the active drug ferric carboxymaltose. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. With anemia, you have a low level of red blood cells (RBCs) in your body. You can also write a reminder on your calendar. Many people using this medication do not have serious side effects. Its not known whether its safe to breastfeed while youre taking Injectafer. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. But for other people, their IDA returns after treatment with Injectafer. The insurance company will review the prior authorization request and decide if the drug will be covered. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. For some people, it may be OK to continue taking a multivitamin that contains iron. Your healthcare provider will watch you closely for 30 minutes after each dose. This is not a complete list of possible side effects. Venofer is not for treating other forms of anemia not caused by iron deficiency. It may also cause nervousness, restlessness, and difficulty sleeping in some people. Injectafer isnt available in a generic form. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). Its not known how often people taking a treatment other than Injectafer had diarrhea. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. No, you most likely wont take Injectafer long term. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. <> Nose or throat irritation. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Best food forward: Are algae the future of sustainable nutrition? We cancelled my 5th because of the reaction. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Pain in your limbs. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. If you have questions about side effects, call your doctor. Weight changes may be due to symptoms of anemia improving. Selected from data included with permission and copyrighted by First Databank, Inc. Once inside your body, ferric carboxymaltose releases iron into your system. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. This is not a complete list of side effects and others may occur. Mental healthdisorders like depression may requireantidepressantsto treat. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. And this person had gotten their first dose of the drug without having an allergic reaction. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. This gives a total cumulative dose of 1,500 mg of Injectafer. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Which tests can diagnose iron deficiency anemia? In one study, people were given either Injectafer or an iron replacement drug called Venofer. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. Theyll recommend how to manage your condition. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Infusion times range from less than 20 minutes to up to 4 hours. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. There have also been reports of serious allergic reactions to Venofer. * This is a partial list of mild side effects from Injectafer. If either is present, do not use the liquid. (For more information on Venofer, see the Injectafer vs. Venofer section above). endobj Is the ketogenic diet right for autoimmune conditions? What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Effectiveness of Injectafer compared with iron thats taken by mouth. Venofer may reduce the absorption of iron preparations taken by mouth. Injectafer infusions are given over a period of at least 15 minutes. Keep all medications away from children and pets. Call your doctor for medical advice about side effects. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. After the infusion, you can drive yourself home and return to your usual activities. They can tell you about other medications that may work well for you. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. But if they become more severe or dont go away, talk with your doctor or pharmacist. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. It is important to get each dose of this medication as scheduled. A shortage of iron can cause health problems. For example: Say you weigh 105 pounds (about 48 kilograms). Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. For additional information, contact your healthcare provider. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. With slow IV injection, the drug is given as a single, slow injection into your vein. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. And this can lead to anemia, including IDA. An iron infusion is a way to increase the body's iron levels quickly. Venofer treatment may be repeated if iron deficiency reoccurs. It can also cause skin irritation and redness. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Hes an expert in genetic testing, genetic analysis, andprecision medicine. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Follow all instructions closely. The following information describes dosages that are commonly used or recommended. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Serious side effects from Injectafer arent common, but they can occur. This medication is given by injection into a vein as directed by your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Keep all drugs in a safe place. Below are examples of these side effects. This means you would get two Injectafer doses of 720 mg each. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Venofer is given as an infusion into a vein. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Mild side effects of Injectafer can include:*. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. intense abdominal pain. Diarrhea. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. It can be given as a slow injection over 2 to 5 minutes or as an infusion. If these effects continue or worsen, tell your doctor. I actually was constipated after my 3rd but didn't think anything of it. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. I had my first infusion of 1gm 10 days ago. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. fever. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. But for other people, their anemia may come back after Injectafer treatment. stream And this could lead to weight gain, if they increase their food intake. What Is the Cost of Whole Genome Sequencing (WGS)? For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. But its only approved for use in people with CKD who may or may not need dialysis. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). There are currently no generic forms of either drug. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Its responsible for carrying oxygen throughout your body. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. This medication is given by injection into a vein as directed by your doctor. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Cancer patients who have anemia and are taking an ESA. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. * Sex and gender exist on spectrums. Injectafer and Feraheme are both brand-name drugs. experience severe side effects, please seek medical attention right away and notify the ordering physician. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Here are answers to some frequently asked questions about Injectafer. But the length of time that this may take varies from person to person. It depends. These are not all the side effects that may occur; contact your healthcare provider if you have questions. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Your doctor will be able to see how Venofer is working by reviewing your blood tests. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. I had Venofer infusions, 2 rounds now in the span of three years. Hemoglobin is a protein thats found in your RBCs. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. This survey is being conducted by the WebMD marketing sciences department. Any long-term side effects/dangers from iron infusions? No, Injectafer itself wont make you gain weight. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. A variety of tests can diagnose iron deficiency anemia. Headache. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Their medical staff can help you set up another time to receive your Injectafer dose. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Serious side effects should be reported to a physician and/or PharmD for medical advice. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Together, you and your doctor can develop a treatment plan thats best for you. However, diarrhea it isnt very common in people using Injectafer. Storage Condition Store in a cool and dry place protected from light. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. These lists dont include all possible side effects. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. (And Injectafer is used to treat IDA.) "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Health careproviderscan provide information on how longside effectslast by checking amedication guide. Medically reviewed by Sanjai Sinha, MD. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Talk to your pharmacist for more details. You may report side effects to FDA at 1-800-FDA-1088. . In the study, peoples hemoglobin level was measured to check for improvement in their anemia. wAd**CgI%"nn{Oa[q{r5 But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia.
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